未破裂腹主动脉瘤的急诊手术。

Annales chirurgiae et gynaecologiae Pub Date : 1999-01-01
S Soisalon-Soininen, J A Salo, V Perhoniemi, S Mattila
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引用次数: 0

摘要

背景和目的:腹主动脉瘤(AAA)疼痛被认为是破裂的前兆,对于有症状的腹主动脉瘤进行急诊手术是一种被广泛接受的预防破裂的做法。为了明确急诊手术的益处,我们评估了急诊治疗的未破裂AAAs患者的临床过程。材料与方法:110例患者(男性90例,平均69岁,范围49 ~ 93岁;1970年至1992年间,20名女性(平均年龄75岁,63-89岁)在赫尔辛基大学中心医院(HUCH)胸外科和心血管外科接受了未破裂AAA的紧急修复。采用产品-极限-生存法分析术后生存率。将年龄分层后的生存率与同期因AAAs破裂而接受择期手术(n=599)或紧急手术(n=363)的患者进行比较。采用logistic回归分析和Cox比例风险模型分析影响术后早期和晚期生存率的危险因素。结果:急诊非破裂组30天手术死亡率为18%(20/110),而择期组为7%(42/599),破裂组为49% (179/363)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Emergency surgery of non-ruptured abdominal aortic aneurysm.

Background and aims: The pain of an abdominal aortic aneurysm (AAA) is believed to signify rupture, and emergency surgery for symptomatic AAA is a widely accepted practice to prevent rupture. To clarify the benefit of emergency surgery we evaluated the clinical course of emergency treated patients with non-ruptured AAAs.

Material and methods: 110 patients (90 men, mean age 69, range 49-93; 20 women, mean age 75, range 63-89) underwent emergency repair of non-ruptured AAA between 1970 and 1992 at the Department of Thoracic and Cardiovascular Surgery of Helsinki University Central Hospital (HUCH). Survival rates after surgery were analysed using product-limit-survivorship method. The survival rates after age-stratification were compared with those of patients undergone elective surgery (n=599) or emergency surgery because of ruptured AAAs (n=363) during the same period. Risk factors affecting early and late survival rates after operation were analysed by logistic regression analysis and Cox proportional hazard model.

Results: Thirty-day operative mortality rates were 18 % (20/110) in the emergency non-ruptured group, compared with 7 % (42/599) in the elective group and 49 % (179/363) in the ruptured group (p<0.05). Thirty day survival rate was not changed among the nonruptured emergency group from 1970 to 1992, whereas the rates of ruptured and elective groups became better during the study period. Late survival rates for 30-day postoperative survivors were clearly reduced among the non-ruptured emergency group, without difference between the emergency operated ruptured and non-ruptured groups. Coronary artery disease was decreasing significantly early and late survival rates after emergency surgery for non-ruptured AAAs (p<0.05, logistic regression and p<0.001 Cox proportional hazard).

Conclusions: Early and late mortality risk is significantly higher (p<0.001) after emergency surgery for haemodynamically stable non-ruptured AAA than after elective surgery, mainly because of coronary artery disease.

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