探索双重诊断的多样性:聚类分析对方案规划的效用。

D A Luke, C T Mowbray, K Klump, S E Herman, B BootsMiller
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引用次数: 15

摘要

本研究展示了利用聚类分析来探讨双重诊断人群的异质性,从而促进个体化治疗方案的规划和实施的效用。通过成瘾严重程度指数(ASI)和其他评估心理、社会和社区功能的措施,对被DSM-III-R精神病诊断和药物滥用问题送入州立精神病院的467人进行了访谈。七个ASI严重程度评分(医疗、就业、酒精、药物、法律、家庭和精神功能)被用于使用聚类分析将患者分为七个同质亚组:最佳功能、不健康酒精滥用、功能性酒精滥用、药物滥用、功能性多重虐待、犯罪多重虐待和不健康多重虐待。聚类的信度和效度被证明使用半裂测试以及横断面和纵向分析。结果说明了双重诊断的极端异质性,并提示如何个性化治疗方案可以匹配双重诊断患者的特殊需求。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploring the diversity of dual diagnosis: utility of cluster analysis for program planning.

This study demonstrates the utility of using cluster analysis to explore the heterogeneity of dual diagnosis populations so as to facilitate planning and implementation of individualized treatment programs. A sample of 467 persons admitted to a state psychiatric hospital with DSM-III-R psychiatric diagnoses and substance abuse problems were interviewed on the Addiction Severity Index (ASI) and other measures to assess psychological, social, and community functioning. Scores on seven ASI severity ratings (medical, employment, alcohol, drug, legal, family, and psychiatric functioning) were used to group patients into seven homogeneous subgroups using cluster analysis: best functioning, unhealthy alcohol abuse, functioning alcohol abuse, drug abuse, functioning polyabuse, criminal polyabuse, and unhealthy polyabuse. Cluster reliability and validity were demonstrated using split-half tests as well as cross-sectional and longitudinal analyses. Results illustrate the extreme heterogeneity of dual diagnosis and are suggestive of how individualized treatment programs can be matched to the particular needs of patients with dual diagnoses.

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