D Thapinta, R A Jenkins, D D Celentano, S Nitayaphan, P Buapunth, A Triampon, P A Morgan, C Khamboonruang, C Suwanarach, Y Yutabootr, S Ruckphaopunt, S Suwankiti, V Tubtong, W Cheewawat, J G McNeil, R A Michael
{"title":"评估泰国HIV疫苗试验志愿者的行为和社会问题。","authors":"D Thapinta, R A Jenkins, D D Celentano, S Nitayaphan, P Buapunth, A Triampon, P A Morgan, C Khamboonruang, C Suwanarach, Y Yutabootr, S Ruckphaopunt, S Suwankiti, V Tubtong, W Cheewawat, J G McNeil, R A Michael","doi":"10.1097/00042560-199903010-00015","DOIUrl":null,"url":null,"abstract":"<p><p>Behavioral and social issues were investigated in phase I/II preventive HIV vaccine trial volunteers in Thailand. These included risk behavior, HIV knowledge, distress, and social experiences associated with trial participation. Data were collected at baseline and at 4- and 8-month follow-up visits. Volunteers reported relatively low levels of risk behaviors at baseline and at the follow-up visits. About one fifth reported overtly negative reactions from family or friends. No problems with discrimination in employment, health care, or insurance were reported. Findings add to the evidence suggesting the feasibility of phase I/II prophylactic HIV vaccine trials with low-risk volunteers in Thailand.</p>","PeriodicalId":14731,"journal":{"name":"Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association","volume":"20 3","pages":"308-14"},"PeriodicalIF":0.0000,"publicationDate":"1999-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/00042560-199903010-00015","citationCount":"33","resultStr":"{\"title\":\"Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers.\",\"authors\":\"D Thapinta, R A Jenkins, D D Celentano, S Nitayaphan, P Buapunth, A Triampon, P A Morgan, C Khamboonruang, C Suwanarach, Y Yutabootr, S Ruckphaopunt, S Suwankiti, V Tubtong, W Cheewawat, J G McNeil, R A Michael\",\"doi\":\"10.1097/00042560-199903010-00015\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Behavioral and social issues were investigated in phase I/II preventive HIV vaccine trial volunteers in Thailand. These included risk behavior, HIV knowledge, distress, and social experiences associated with trial participation. Data were collected at baseline and at 4- and 8-month follow-up visits. Volunteers reported relatively low levels of risk behaviors at baseline and at the follow-up visits. About one fifth reported overtly negative reactions from family or friends. No problems with discrimination in employment, health care, or insurance were reported. Findings add to the evidence suggesting the feasibility of phase I/II prophylactic HIV vaccine trials with low-risk volunteers in Thailand.</p>\",\"PeriodicalId\":14731,\"journal\":{\"name\":\"Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association\",\"volume\":\"20 3\",\"pages\":\"308-14\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1999-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1097/00042560-199903010-00015\",\"citationCount\":\"33\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/00042560-199903010-00015\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/00042560-199903010-00015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers.
Behavioral and social issues were investigated in phase I/II preventive HIV vaccine trial volunteers in Thailand. These included risk behavior, HIV knowledge, distress, and social experiences associated with trial participation. Data were collected at baseline and at 4- and 8-month follow-up visits. Volunteers reported relatively low levels of risk behaviors at baseline and at the follow-up visits. About one fifth reported overtly negative reactions from family or friends. No problems with discrimination in employment, health care, or insurance were reported. Findings add to the evidence suggesting the feasibility of phase I/II prophylactic HIV vaccine trials with low-risk volunteers in Thailand.
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