六种呼吸器适合性测试方法与模拟医疗保健环境中实际暴露测量的比较:第2部分——方法比较测试

C C Coffey, D L Campbell, W R Myers, Z Zhuang
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引用次数: 36

摘要

本文是三篇系列文章中的第二篇,描述了一项研究的方法比较测试部分,该研究将六次定量适合测试(QNFT)的适合因素与在相同条件下通过呼气末空气分析评估的呼吸器佩戴者的实际暴露量进行比较。六种QNFT方法分别是:(1)连续低流量、冲洗探针;(2)连续高流量、深探头(CHD);(3)呼气阀排出量(EVD);(4)控制负压;(5) 10分钟大气气溶胶1 (AA1);(6) 30分钟环境气溶胶2。前三种方法使用玉米油和前向光散射光度计。最后两种方法使用了TSI portaccount。研究中使用的呼吸器既有一次性的,也有弹性有机蒸汽/高效半面罩。在方法比较试验中,利用初步研究(前文所述)的表征方程来确定氟利昂-113的实际暴露量。然后使用决定系数R2将QNFT方法得出的拟合因子与氟利昂-113暴露单独相关。EVD法的R2值最低,为0.20。CHD和AA1方法的R2值最高,分别为0.81和0.78。这项研究表明,一些QNFT方法可以用来估计实验室条件下的实际呼吸器性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of six respirator fit-test methods with an actual measurement of exposure in a simulated health care environment: Part II--Method comparison testing.

This article, the second in a series of three, describes the method comparison testing portion of a study conducted to compare the fit factors from six quantitative fit-tests (QNFT) with a measure of a respirator wearer's actual exposure assessed by end-exhaled air analysis for 1,1,2-trichloro-1,2,2-trifluoroethane (Freon-113) under the same conditions. The six QNFT methods were (1) continuous low flow, flush probe; (2) continuous high flow, deep probe (CHD); (3) exhalation valve discharge (EVD); (4) controlled negative pressure; (5) 10-minute Ambient Aerosol 1 (AA1); and (6) 30-minute Ambient Aerosol 2. The first three methods utilized corn oil and a forward light scattering photometer. The last two methods used the TSI Portacount. Respirators used in the study were both disposable and elastomeric organic vapor/high efficiency half-masks. The characterization equations from the preliminary research (described previously) were used to determine the actual exposure to Freon-113 during the method comparison testing. The fit factors resulting from the QNFT methods were then individually correlated with the Freon-113 exposures using the coefficient of determination, R2. The lowest R2 value, 0.20, was found with the EVD method. The highest R2 values, 0.81 and 0.78, were associated, respectively, with the CHD and AA1 methods. This study suggests that some QNFT methods may be used to estimate actual respirator performance under laboratory conditions.

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