{"title":"钙结合蛋白和一氧化氮在视网膜功能和疾病中的作用。","authors":"F Müller, K W Koch","doi":"10.1159/000046479","DOIUrl":null,"url":null,"abstract":"<p><p>Regulation of phototransduction in photoreceptor cells occurs via several feedback loops. Some of these circuits involve the neuron-specific Ca2+-binding proteins recoverin and guanylyl cyclase-activating protein. Recent findings suggest that these proteins are also involved in retinal diseases. Another Ca2+-regulated process in the retina is the synthesis of nitric oxide, a substance of potential neurotoxicity. This review discusses several Ca2+-mediated processes in the retina.</p>","PeriodicalId":6885,"journal":{"name":"Acta anatomica","volume":"162 2-3","pages":"142-50"},"PeriodicalIF":0.0000,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000046479","citationCount":"10","resultStr":"{\"title\":\"Calcium-binding proteins and nitric oxide in retinal function and disease.\",\"authors\":\"F Müller, K W Koch\",\"doi\":\"10.1159/000046479\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Regulation of phototransduction in photoreceptor cells occurs via several feedback loops. Some of these circuits involve the neuron-specific Ca2+-binding proteins recoverin and guanylyl cyclase-activating protein. Recent findings suggest that these proteins are also involved in retinal diseases. Another Ca2+-regulated process in the retina is the synthesis of nitric oxide, a substance of potential neurotoxicity. This review discusses several Ca2+-mediated processes in the retina.</p>\",\"PeriodicalId\":6885,\"journal\":{\"name\":\"Acta anatomica\",\"volume\":\"162 2-3\",\"pages\":\"142-50\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1998-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1159/000046479\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta anatomica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000046479\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta anatomica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000046479","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Calcium-binding proteins and nitric oxide in retinal function and disease.
Regulation of phototransduction in photoreceptor cells occurs via several feedback loops. Some of these circuits involve the neuron-specific Ca2+-binding proteins recoverin and guanylyl cyclase-activating protein. Recent findings suggest that these proteins are also involved in retinal diseases. Another Ca2+-regulated process in the retina is the synthesis of nitric oxide, a substance of potential neurotoxicity. This review discusses several Ca2+-mediated processes in the retina.
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