{"title":"γ辐射对Li+通过人红细胞膜转运的影响。","authors":"C Bindea, V V Morariu, I Chereji","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Human erythrocytes were exposed at room temperatures to 662 keV gamma radiation at doses up to 60 Gy. The total delta Li+ influx as well as the delta Li+ influx by passive diffusion and Na(+)-K+ pump mechanisms increased linearly with the dose. The rate constant K of Li+ efflux by the Li(+)-Na+ countertransport mechanism through irradiated erythrocyte membranes was reduced by about 35% at the highest dose.</p>","PeriodicalId":11078,"journal":{"name":"Cytobios","volume":"93 372","pages":"23-31"},"PeriodicalIF":0.0000,"publicationDate":"1998-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effect of gamma radiation on Li+ transport through human erythrocyte membranes.\",\"authors\":\"C Bindea, V V Morariu, I Chereji\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Human erythrocytes were exposed at room temperatures to 662 keV gamma radiation at doses up to 60 Gy. The total delta Li+ influx as well as the delta Li+ influx by passive diffusion and Na(+)-K+ pump mechanisms increased linearly with the dose. The rate constant K of Li+ efflux by the Li(+)-Na+ countertransport mechanism through irradiated erythrocyte membranes was reduced by about 35% at the highest dose.</p>\",\"PeriodicalId\":11078,\"journal\":{\"name\":\"Cytobios\",\"volume\":\"93 372\",\"pages\":\"23-31\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1998-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Cytobios\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cytobios","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effect of gamma radiation on Li+ transport through human erythrocyte membranes.
Human erythrocytes were exposed at room temperatures to 662 keV gamma radiation at doses up to 60 Gy. The total delta Li+ influx as well as the delta Li+ influx by passive diffusion and Na(+)-K+ pump mechanisms increased linearly with the dose. The rate constant K of Li+ efflux by the Li(+)-Na+ countertransport mechanism through irradiated erythrocyte membranes was reduced by about 35% at the highest dose.