正常衰老导致的肾功能下降是必然的吗?

Geriatric nephrology and urology Pub Date : 1998-01-01 DOI:10.1023/a:1008294000258

R D Lindeman

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引用次数: 26

摘要

在正常衰老的肾脏中观察到的结构变化支持了一个概念，即随着年龄的增长，肾功能应该会下降。然而，肾脏生理学家的报告表明，这并不总是正确的。这表明血管对结构变化的适应可能通过在存活的肾单位中产生高灌注和高滤过状态来帮助保持肾小球滤过率。

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Is the decline in renal function with normal aging inevitable?

The structural changes observed in the normal aging kidney support a concept that one should expect a decline in renal function as one ages. Reports by renal physiologists, however, suggest that this is not always true. The suggestion is made that vascular adaptations to structural changes may help to preserve glomerular filtration rate by producing a state of hyperperfusion and hyperfiltration in surviving nephrons.

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Geriatric nephrology and urology

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