[shoo -saiko-to致急性嗜酸性肺炎1例]。

Nihon Kyobu Shikkan Gakkai zasshi Pub Date : 1997-12-01
Y Kobashi, M Nakajima, Y Niki, T Matsushima
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引用次数: 0

摘要

一名16岁的男孩服用了一种含有shosaiko -to的普通非处方感冒药,出现发烧、严重咳嗽、咳痰和呼吸困难。两天后,因胸片见密度负影,肺水肿样影入院。强烈怀疑诊断为药物性肺炎,因为动脉血气分析显示严重低氧血症和白细胞增多伴嗜酸性粒细胞增多,胸部x线片显示双侧弥漫性负密度肺水肿影。经支气管肺活检标本镜检结果与嗜酸性粒细胞性肺炎相符。支气管肺泡灌洗液中嗜酸性粒细胞百分比高。淋巴细胞刺激试验结果为shosaiko -to阳性,强烈怀疑是shosaiko -to引起的肺炎。病人停止服用感冒药,并给予强的松龙。临床症状、严重低氧血症和胸部x线表现明显改善。据我们所知,以前没有报道过由shoo -saiko- To引起的急性嗜酸性肺炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[A case of acute eosinophilic pneumonia due to Sho-saiko-to].

A 16-year-boy who had taken a common over-the-counter cold remedy containing Sho-saiko-to, presented with fever, severe cough, sputum and dyspena. Two days later, he was admitted because a negative density, pulmonary edema-like shadow was noted on chest X-ray. A diagnosis of drug-induced pneumonia was strongly suspected, because an arterial blood gas analysis showed severe hypoxemia and leukocytosis with eosinophilia, and the chest X-ray showed a diffuse negative density pulmonary edema like shadow bilaterally. The findings on microscopic examination of transbronchial lung biopsy specimens were compatible with eosinophilic pneumonia. The eosinophil percentage in the bronchoalveolar lavage fluid was high. The result of a lymphocyte-stimulation test was positive for Sho-saiko-to, and Sho-saiko-to-induced pneumonia was strongly suspected. The patient ceased taking the cold remedy, and prednisolone was given. The clinical symptoms, severe hypoxemia, and chest X-ray findings markedly improved. To the best of our knowledge, there have been no previous reports of acute eosinophilic pneumonia induced by Sho-saiko-to.

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