集成到全尺寸患者模拟器的颅内动力学计算机模型

William James Thoman, Samsun Lampotang, Dietrich Gravenstein, Jan van der Aa
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引用次数: 14

摘要

在模拟临床场景中可视化颅内动态的能力是教授脑生理学和不同医疗干预对大脑的影响的宝贵工具。研究已经分离出生理变量,并显示了它们对大脑动力学的影响。然而,没有研究表明这些变量对颅内动力学的综合影响。这个大脑模型提供了一种方法,将所有这些关系结合在一起,并展示了它们如何影响大脑的动态。大脑模型从对临床干预作出反应的全尺寸患者模拟器获得其生理输入。这种整合使得在病人模拟器上工作的个人可以看到他们的行为对大脑动力学的影响。该脑模型实时显示颅内事件(脑代谢率、脑血流量、脑血容量、脑灌注压和颅内压),并响应患者模拟器肺部和心血管状况的变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Computer Model of Intracranial Dynamics Integrated to a Full-Scale Patient Simulator

The ability to visualize intracranial dynamics during simulated clinical scenarios is a valuable tool for teaching brain physiology and the consequences of different medical interventions on the brain. Studies have isolated physiologic variables and shown their effects on brain dynamics. However, no studies have shown the combined effects of these variables on intracranial dynamics. This brain model offers one approach that brings all these relationships together and shows how they affect the dynamics of the brain. The brain model obtains its physiologic inputs from a full-scale patient simulator which responds to clinical interventions. This integration allows individuals working on the patient simulator to see the effects of their actions on brain dynamics. The brain model gives a real-time display of intracranial events (cerebral metabolic rate, cerebral blood flow, cerebral blood volume, cerebral perfusion pressure, and intracranial pressure) and responds to changes in the pulmonary and cardiovascular condition of the patient simulator.

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