蛛网膜下腔出血的外科治疗。

New horizons (Baltimore, Md.) Pub Date : 1997-11-01
M H Brisman, J B Bederson
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引用次数: 0

摘要

自发性蛛网膜下腔出血通常是由脑动脉瘤破裂引起的。动脉瘤破裂通常表现为突然的剧烈头痛,常伴有精神状态的改变。诊断是通过计算机断层扫描或腰椎穿刺。脑动脉瘤破裂的患者有再出血、脑动脉血管痉挛(以及随后的缺血或中风)和脑积水的风险。在显微镜下早期手术切除动脉瘤通常是首选的治疗方法。该手术可防止再出血,并允许在临床血管痉挛发生时安全使用降压药。支持延迟手术、“盘绕”手术或保守治疗的因素包括患者状况不佳、基底动脉动脉瘤和异常大或不规则的动脉瘤。动脉瘤破裂的患者用尼莫地平(一种钙通道阻滞剂)治疗,以帮助预防血管痉挛相关的缺血。除临床检查外,通过经颅多普勒超声和脑血管造影评估动脉瘤破裂后前2周血管痉挛的程度。有症状性血管痉挛的患者应保持充足的水分,并使用降压药治疗(前提是动脉瘤已成功切除)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical management of subarachnoid hemorrhage.

Spontaneous subarachnoid hemorrhage is usually caused by a ruptured cerebral aneurysm. Aneurysmal rupture classically presents with sudden severe headache, often accompanied by an altered mental status. Diagnosis is made with computed tomography or lumbar puncture. Patients with ruptured cerebral aneurysms are at risk for rebleeding, cerebral artery vasospasm (and subsequent ischemia or stroke), and hydrocephalus. Early surgical clipping of the aneurysm under the microscope is usually the initial treatment of choice. This surgery prevents rebleeding and allows for safe use of pressors in the event that clinical vasospasm develops. Factors that would favor delayed surgery, "coiling" procedures, or conservative management include poor patient condition, basilar artery aneurysms, and unusually large or irregular aneurysms. Patients with ruptured aneurysms are treated with nimodipine, a calcium-channel blocker, to help prevent vasospasm-related ischemia. The degree of vasospasm that develops in the first 2 wks after aneurysmal rupture is assessed by transcranial Doppler sonography and cerebral angiography, in addition to the clinical examination. Patients with symptomatic vasospasm are kept well hydrated and treated with pressors (provided the aneurysm has been successfully clipped).

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