老年动脉粥样硬化性肾血管疾病:血管成形术与支架植入与重建手术。

S Bhandari, A Wilkinson, A Nicholson, M J Farr, L Sellars
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引用次数: 3

摘要

我们回顾了1987年至1994年间43例肾血管造影疾病的手术和放射治疗经验。我们回顾性比较了血管成形术合并支架置入与重建手术对明显动脉粥样硬化性肾血管狭窄患者肾功能和血压的影响。20例中度/非口狭窄(狭窄小于60%)患者和2例纤维肌肉发育不良患者仅行肾血管成形术。干预的指征是难治性高血压(n = 20),突发性肺水肿(n = 8)和/或肾保留(n = 31)。所有患者均为高血压。10例患者行血管成形术合并支架植入术,其中2例女性,8例男性,平均年龄69岁,9例双侧病变。7例患者血浆肌酐大于240 μ mol/L。9例患者行单侧手术。11例患者行单侧重建手术,其中女性4例,男性7例,平均年龄63岁。8例患者血浆肌酐大于240 μ mol/L。10例双侧病变。血管成形术/支架置入术组出现3次技术失败。血管成形术/支架置入术组和手术组的死亡率分别为10%和27%。支架组和手术组分别经过51个月和165个月。各组血压均下降,平均动脉压(MAP)分别下降16 mmHg (p = 0.025)和30 mmHg (p < 0.01)。67%和91%的患者肾功能得到改善或稳定。两名手术患者能够停止血液透析。这两种治疗方法在降低血压方面似乎同样有效。重建手术提供了更大的肾功能改善,并有可能停止透析,但代价是死亡率较高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Atherosclerotic renovascular disease in the elderly: angioplasty with stenting versus reconstructive surgery.

We reviewed our experience of surgical and radiological intervention in 43 patients between 1987 and 1994 with angiographic renovascular disease. We retrospectively compared the effect of angioplasty with stenting versus reconstructive surgery on renal function and blood pressure in those patients with significant atherosclerotic renovascular stenosis. Twenty patients with moderate/non ostial stenosis (less than 60% stenosis) and two with fibromuscular displasia underwent renal angioplasty only. Indications for intervention were refractory hypertension (n = 20), flash pulmonary oedema (n = 8) and/or renal salvage (n = 31). All patients were hypertensive. Angioplasty with stenting was performed in ten patients, (2 female, 8 male), mean age 69 years, 9 with bilateral disease. Plasma creatinine was greater than 240 mumol/L in seven patients. A unilateral procedure was performed in 9 patients. Unilateral reconstructive surgery was performed in eleven patients (4 female, 7 male), mean age 63 years. Plasma creatinine was greater than 240 mumol/L in eight patients. Ten had bilateral disease. In the angioplasty/stenting group there were three technical failure. The mortality rates in the angioplasty/stenting group and surgical group were 10% and 27% respectively. Fifty-one and 165 patient months had elapsed in the stenting and surgical groups respectively. Blood pressure fell in each group, mean decrease in mean arterial pressure (MAP) 16 mmHg (p = 0.025) and 30 mmHg (p < 0.01) respectively. Improvement or stabilisation of renal function was achieved in 67% and 91% of cases respectively. Two surgical patients were able to discontinue haemodialysis. The two methods of treatment appear to be equally effective in lowering blood pressure. Reconstructive surgery offers greater improvement in renal function with the possibility of withdrawal of dialysis, at the expense of a higher mortality rate.

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