MD Jean-Pierre Devogelaer (Professor and Head of Arthritis Unit)
{"title":"你如何知道谁需要预防或治疗?","authors":"MD Jean-Pierre Devogelaer (Professor and Head of Arthritis Unit)","doi":"10.1016/S0950-3579(97)80019-2","DOIUrl":null,"url":null,"abstract":"<div><p>Osteoporosis is preventable with the various therapeutic options available today. It is therefore important to reach the patient who needs to be treated. If based only on clinical risk factors there is much room for therapeutic misassignation in both directions: too many and too few treatments. Generally speaking, only bone mass measurement can yield the correct risk for future fracture, and clinical factors taken alone might be misleading. Clinical factors can be used to modulate the therapeutic intervention based on assessment of bone mass. In very elderly people with several risk factors (poor vision, poor balance and awkward gait, use of psychotropic drugs, etc), bone mass measurements probably become less crucial in therapeutic decision, because factors other than bone mineral have also to be actively assessed. All in all, the use of cut offs of bone mineral density balanced with the clinical decision based on an individual examination, will allow assessment of the therapeutic level in a particular patient. A therapeutic intervention will never be an all or nothing phenomenon based on computerized data.</p></div>","PeriodicalId":77032,"journal":{"name":"Bailliere's clinical rheumatology","volume":"11 3","pages":"Pages 539-563"},"PeriodicalIF":0.0000,"publicationDate":"1997-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0950-3579(97)80019-2","citationCount":"5","resultStr":"{\"title\":\"5 How do you know who needs prevention or treatment?\",\"authors\":\"MD Jean-Pierre Devogelaer (Professor and Head of Arthritis Unit)\",\"doi\":\"10.1016/S0950-3579(97)80019-2\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Osteoporosis is preventable with the various therapeutic options available today. It is therefore important to reach the patient who needs to be treated. If based only on clinical risk factors there is much room for therapeutic misassignation in both directions: too many and too few treatments. Generally speaking, only bone mass measurement can yield the correct risk for future fracture, and clinical factors taken alone might be misleading. Clinical factors can be used to modulate the therapeutic intervention based on assessment of bone mass. In very elderly people with several risk factors (poor vision, poor balance and awkward gait, use of psychotropic drugs, etc), bone mass measurements probably become less crucial in therapeutic decision, because factors other than bone mineral have also to be actively assessed. All in all, the use of cut offs of bone mineral density balanced with the clinical decision based on an individual examination, will allow assessment of the therapeutic level in a particular patient. A therapeutic intervention will never be an all or nothing phenomenon based on computerized data.</p></div>\",\"PeriodicalId\":77032,\"journal\":{\"name\":\"Bailliere's clinical rheumatology\",\"volume\":\"11 3\",\"pages\":\"Pages 539-563\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1997-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/S0950-3579(97)80019-2\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bailliere's clinical rheumatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0950357997800192\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bailliere's clinical rheumatology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0950357997800192","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
5 How do you know who needs prevention or treatment?
Osteoporosis is preventable with the various therapeutic options available today. It is therefore important to reach the patient who needs to be treated. If based only on clinical risk factors there is much room for therapeutic misassignation in both directions: too many and too few treatments. Generally speaking, only bone mass measurement can yield the correct risk for future fracture, and clinical factors taken alone might be misleading. Clinical factors can be used to modulate the therapeutic intervention based on assessment of bone mass. In very elderly people with several risk factors (poor vision, poor balance and awkward gait, use of psychotropic drugs, etc), bone mass measurements probably become less crucial in therapeutic decision, because factors other than bone mineral have also to be actively assessed. All in all, the use of cut offs of bone mineral density balanced with the clinical decision based on an individual examination, will allow assessment of the therapeutic level in a particular patient. A therapeutic intervention will never be an all or nothing phenomenon based on computerized data.