意大利某省HLA基因频率和迁移。

Gene geography : a computerized bulletin on human gene frequencies Pub Date : 1996-12-01

A De Silvestri, M Martinetti, C Daielli, L Salvaneschi, M Cuccia, C R Guglielmino

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摘要

对帕维亚省6个亚区2份骨髓供者样本的HLAⅰ类(HLA- a、HLA- b)和ⅱ类(HLA- dr、HLA- dq)基因频率进行了计算。通过标准化方差FST估计6个子区域间的遗传分化程度。在岛屿移徙模型的基础上，根据FST估计移徙人数，并与根据1991年人口普查在该省观察到的移徙指数进行比较。

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HLA gene frequencies and migration in an Italian province.

HLA class I (HLA-A, HLA-B) and class II (HLA-DR, HLA-DQ) gene frequencies in 6 subareas of Pavia province are calculated in two samples of bone marrow donors. We estimated the degree of genetic differentiation between the 6 sub-areas through the standardized variance FST. On the basis of the island migration model the number of migrants is estimated from FST and compared with the observed migration index in the province according to the 1991 census.

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Gene geography : a computerized bulletin on human gene frequencies

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