{"title":"用TREECON for Windows构建进化距离树:考虑位点间核苷酸取代率的变化。","authors":"Y Van de Peer, R De Wachter","doi":"10.1093/bioinformatics/13.3.227","DOIUrl":null,"url":null,"abstract":"<p><strong>Motivation: </strong>To improve the estimation of evolutionary distances between nucleotide sequences by considering the differences in substitution rates among sites.</p><p><strong>Results: </strong>TREECON for Windows (Van de Peer,Y. and De Wachter,R. Comput. Applic. Biosci., 9, 569-570, 1994) is a software package for the construction and drawing of phylogenetic trees based on distance data computed from nucleic acid and amino acid sequences. For nucleic acids, we here describe the implementation of a recently developed method for estimating evolutionary distances taking into account the substitution rate of individual sites in a sequence alignment.</p><p><strong>Availability: </strong>TREECON for Windows is available on request from the authors. A small fee is asked in order to support the work and to reinvest in new computer hard- and software. More information about the program and substitution rate calibration can be found at URL http:/(/)bioc-www.uia.ac.be/u/ yvdp/treeconw.html.</p>","PeriodicalId":77081,"journal":{"name":"Computer applications in the biosciences : CABIOS","volume":"13 3","pages":"227-30"},"PeriodicalIF":0.0000,"publicationDate":"1997-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/bioinformatics/13.3.227","citationCount":"326","resultStr":"{\"title\":\"Construction of evolutionary distance trees with TREECON for Windows: accounting for variation in nucleotide substitution rate among sites.\",\"authors\":\"Y Van de Peer, R De Wachter\",\"doi\":\"10.1093/bioinformatics/13.3.227\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Motivation: </strong>To improve the estimation of evolutionary distances between nucleotide sequences by considering the differences in substitution rates among sites.</p><p><strong>Results: </strong>TREECON for Windows (Van de Peer,Y. and De Wachter,R. Comput. Applic. Biosci., 9, 569-570, 1994) is a software package for the construction and drawing of phylogenetic trees based on distance data computed from nucleic acid and amino acid sequences. For nucleic acids, we here describe the implementation of a recently developed method for estimating evolutionary distances taking into account the substitution rate of individual sites in a sequence alignment.</p><p><strong>Availability: </strong>TREECON for Windows is available on request from the authors. A small fee is asked in order to support the work and to reinvest in new computer hard- and software. More information about the program and substitution rate calibration can be found at URL http:/(/)bioc-www.uia.ac.be/u/ yvdp/treeconw.html.</p>\",\"PeriodicalId\":77081,\"journal\":{\"name\":\"Computer applications in the biosciences : CABIOS\",\"volume\":\"13 3\",\"pages\":\"227-30\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1997-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1093/bioinformatics/13.3.227\",\"citationCount\":\"326\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Computer applications in the biosciences : CABIOS\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/bioinformatics/13.3.227\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer applications in the biosciences : CABIOS","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/bioinformatics/13.3.227","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 326
摘要
动机:通过考虑位点间取代率的差异，提高对核苷酸序列之间进化距离的估计。结果:TREECON for Windows (Van de Peer,Y。以及R. De Wachter。第一版。品。Biosci。， 9,569 -570, 1994)是一个基于从核酸和氨基酸序列计算的距离数据构建和绘制系统发育树的软件包。对于核酸，我们在这里描述了一种最近开发的方法，用于估计进化距离，考虑到序列比对中单个位点的取代率。可用性:TREECON for Windows可根据作者的要求提供。为了支持这项工作和重新投资新的计算机硬件和软件，会收取一小笔费用。关于程序和替代率校准的更多信息可以在URL上找到:/(/)bioc-www.uia.ac.be/u/ yvdp/treeconw.html。
Construction of evolutionary distance trees with TREECON for Windows: accounting for variation in nucleotide substitution rate among sites.
Motivation: To improve the estimation of evolutionary distances between nucleotide sequences by considering the differences in substitution rates among sites.
Results: TREECON for Windows (Van de Peer,Y. and De Wachter,R. Comput. Applic. Biosci., 9, 569-570, 1994) is a software package for the construction and drawing of phylogenetic trees based on distance data computed from nucleic acid and amino acid sequences. For nucleic acids, we here describe the implementation of a recently developed method for estimating evolutionary distances taking into account the substitution rate of individual sites in a sequence alignment.
Availability: TREECON for Windows is available on request from the authors. A small fee is asked in order to support the work and to reinvest in new computer hard- and software. More information about the program and substitution rate calibration can be found at URL http:/(/)bioc-www.uia.ac.be/u/ yvdp/treeconw.html.
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