附睾阴离子分泌的旁分泌/自分泌调节:血管紧张素II的作用。

H C Chan, P Y Wong
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引用次数: 7

摘要

越来越多的证据表明,附睾阴离子分泌除受神经和体液调节外,还可能受局部旁分泌/自分泌控制。本文综述了近年来有关大鼠附睾组织肾素-血管紧张素系统主要成分存在的证据以及血管紧张素II (Ang II)对附睾阴离子分泌的调节作用。讨论了angii的局部生成机制及其局部作用。Ang II在维持附睾功能和精子功能中的旁分泌/自分泌作用的重要性也得到了解决。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Paracrine/autocrine regulation of anion secretion in the epididymis: role of angiotensin II.

Accumulated evidence has suggested that anion secretion in the epididymis may be subject to local paracrine/autocrine control in addition to neural and humoral regulation. The present paper reviews recent studies presenting evidence for the presence of major components of a tissue renin-angiotensin system in the rat epididymis and the regulatory effect of angiotensin II (Ang II) on epididymal anion secretion. The mechanisms for local generation of Ang II and its local action are discussed. The importance of paracrine/autocrine roles of Ang II in the maintenance of epididymal functions, as well as sperm functions is also addressed.

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