[picrotoxin诱导的癫痫活动对camp依赖性突触素- 1磷酸化的影响]。

V I Arkhipov, T G Shilakina
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引用次数: 0

摘要

Picrotoxin给药可减少体外皮层神经特异性蛋白synapsin I中标记磷酸盐的掺入。在动物海马中,掺入蛋白表达较多。获得的数据表明,camp依赖性磷酸化的激活发生在癫痫发作期间的皮层。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The effect of picrotoxin-induced seizure activity on the cAMP-dependent phosphorylation of synapsin-I in rats].

Picrotoxin administration decreased the incorporation of labelled phosphate in neurospecific protein synapsin I in vitro in cortex. In the animal hippocampus, the incorporation was more expressed. The data obtained suggest that activation of the cAMP-dependent phosphorylation occurs during seizure in the cortex.

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