{"title":"[5 -羟色胺能系统参与调节中枢谷氨酸/天冬氨酸和氨基丁酸能突触的活动]。","authors":"I P Grigor'ev, A A Neokesariĭskiĭ, V A Otellin","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Selective lesion of the serotoninergic system diminished the synaptic uptake of 3H-L-glutamic acid and 3H-DL-aspartic acid, as well as the Na+(-dependent) binding of 3H-L-glutamic acid in the cortex and the brain stem. The data obtained suggest an ability of the serotoninergic system to modify presynaptic processes in amino-acidergic neurons of the CNS.</p>","PeriodicalId":77130,"journal":{"name":"Fiziologicheskii zhurnal imeni I.M. Sechenova","volume":"82 8-9","pages":"22-7"},"PeriodicalIF":0.0000,"publicationDate":"1996-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The participation of the serotoninergic system in regulating the activity of the central glutamatergic/aspartatergic and GABA-ergic synapses].\",\"authors\":\"I P Grigor'ev, A A Neokesariĭskiĭ, V A Otellin\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Selective lesion of the serotoninergic system diminished the synaptic uptake of 3H-L-glutamic acid and 3H-DL-aspartic acid, as well as the Na+(-dependent) binding of 3H-L-glutamic acid in the cortex and the brain stem. The data obtained suggest an ability of the serotoninergic system to modify presynaptic processes in amino-acidergic neurons of the CNS.</p>\",\"PeriodicalId\":77130,\"journal\":{\"name\":\"Fiziologicheskii zhurnal imeni I.M. Sechenova\",\"volume\":\"82 8-9\",\"pages\":\"22-7\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Fiziologicheskii zhurnal imeni I.M. Sechenova\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fiziologicheskii zhurnal imeni I.M. Sechenova","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
5 -羟色胺能系统的选择性损伤减少了3h - l -谷氨酸和3h - dl -天冬氨酸的突触摄取，以及3h - l -谷氨酸在皮层和脑干的Na+(依赖)结合。所获得的数据表明，血清素能系统能够改变中枢神经系统氨基酸能神经元的突触前过程。
[The participation of the serotoninergic system in regulating the activity of the central glutamatergic/aspartatergic and GABA-ergic synapses].
Selective lesion of the serotoninergic system diminished the synaptic uptake of 3H-L-glutamic acid and 3H-DL-aspartic acid, as well as the Na+(-dependent) binding of 3H-L-glutamic acid in the cortex and the brain stem. The data obtained suggest an ability of the serotoninergic system to modify presynaptic processes in amino-acidergic neurons of the CNS.
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