[手术前几周进行红细胞穿刺:程序性自体输血中红细胞生成素治疗的替代方法]。

Cahiers d'anesthesiologie Pub Date : 1996-01-01
J Bernière, I Gerota
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引用次数: 0

摘要

采用降压、等容血稀释、自体输血和围手术期补血等常规方法,可显著减少出血性手术中异体输血的需要,也可降低感染源传播的风险。促红细胞生成素(EPO)可用于术前自体献血刺激红细胞再生。在急性贫血中,许多研究表明,内源性促红细胞生成素产生的刺激可能非常高,并加速红细胞的产生。采血量高于平时可诱导内源性促红细胞生成素的分泌,可作为自体献血中使用外源性促红细胞生成素的替代方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Erythrocytapheresis a few weeks before surgery: an alternative to erythropoietin treatment in programmed autologous transfusion].

The usual methods like hypotension, isovolaemic haemodilution, autologous transfusion and peri-operative blood salvage may significantly reduce the need for homologous blood transfusion in haemorrhagic surgery and also the risk of transmitting infectious agents. Erythropoietin (EPO) is now available and is used to stimulate red cell regeneration in pre-operative autologous blood donation. In acute anaemia, many studies have shown that the stimulation of endogenous erythropoietin production could be very high and accelerate red blood cell production. Taking higher quantities of blood than usual induces a secretion of endogenous erythropoietin, and could be an alternative for the utilization of exogenous EPO in autologous blood donation.

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