{"title":"博洛尼亚人群中磷酸乙醇酸磷酸酶多态性(PGP):一种快速方法和世界基因频率分析。","authors":"L Castrì, D Luiselli, G Gruppioni","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>PGP electrophoretic polymorphism was studied in a sample of 548 blood donors from the province of Bologna, Italy. Haemolysates were typed by thin starch-gel electrophoresis, a modification of Barker and Hopkinson's method [1978]. The distribution of PGP phenotypes and gene frequencies in Italy varies considerably. The pattern observed in the Bologna sample agrees with the data from northern Italian regions and comparisons show that PGP*2 and PGP*3 gene frequencies tend to decrease along a north-south cline. Sardinia shows a peculiar distribution of gene frequencies where the PGP*2 allele is very low and the PGP*3 allele is absent. The world PGP gene frequencies appear to be distributed along a north-south cline.</p>","PeriodicalId":77141,"journal":{"name":"Gene geography : a computerized bulletin on human gene frequencies","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1996-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Phosphoglycolate phosphatase polymorphism (PGP) in the Bologna population: a rapid method and an analysis of world gene frequencies.\",\"authors\":\"L Castrì, D Luiselli, G Gruppioni\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>PGP electrophoretic polymorphism was studied in a sample of 548 blood donors from the province of Bologna, Italy. Haemolysates were typed by thin starch-gel electrophoresis, a modification of Barker and Hopkinson's method [1978]. The distribution of PGP phenotypes and gene frequencies in Italy varies considerably. The pattern observed in the Bologna sample agrees with the data from northern Italian regions and comparisons show that PGP*2 and PGP*3 gene frequencies tend to decrease along a north-south cline. Sardinia shows a peculiar distribution of gene frequencies where the PGP*2 allele is very low and the PGP*3 allele is absent. The world PGP gene frequencies appear to be distributed along a north-south cline.</p>\",\"PeriodicalId\":77141,\"journal\":{\"name\":\"Gene geography : a computerized bulletin on human gene frequencies\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1996-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Gene geography : a computerized bulletin on human gene frequencies\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Gene geography : a computerized bulletin on human gene frequencies","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Phosphoglycolate phosphatase polymorphism (PGP) in the Bologna population: a rapid method and an analysis of world gene frequencies.
PGP electrophoretic polymorphism was studied in a sample of 548 blood donors from the province of Bologna, Italy. Haemolysates were typed by thin starch-gel electrophoresis, a modification of Barker and Hopkinson's method [1978]. The distribution of PGP phenotypes and gene frequencies in Italy varies considerably. The pattern observed in the Bologna sample agrees with the data from northern Italian regions and comparisons show that PGP*2 and PGP*3 gene frequencies tend to decrease along a north-south cline. Sardinia shows a peculiar distribution of gene frequencies where the PGP*2 allele is very low and the PGP*3 allele is absent. The world PGP gene frequencies appear to be distributed along a north-south cline.