卵中的环adp核糖和钙信号。

Biological signals Pub Date : 1996-03-01 DOI:10.1159/000109179

H C Lee

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引用次数: 27

摘要

环adp核糖是一种具有Ca2+信号功能的环核苷酸。它最初是在海胆卵中发现的，后来被证明在多种细胞中都很活跃。最近在卵中描述的另一种Ca2+释放机制是由烟酸二核苷酸磷酸盐介导的，这是NADP+的衍生物。本文综述了这两种不依赖于三磷酸肌醇的新型Ca(2+)动员途径的最新研究结果。

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Cyclic ADP-ribose and calcium signaling in eggs.

Cyclic ADP-ribose is a cyclic nucleotide with Ca2+ signaling functions. It was first discovered in sea urchin eggs and has since been shown to be active in a variety of cells. Another Ca2+ release mechanism recently described in the eggs is mediated by nicotinic acid dinucleotide phosphate, a derivative of NADP+. This article summarizes current results on these two novel Ca(2+)-mobilizing pathways that are independent of inositol trisphosphate.

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Biological signals

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