实验性旋毛虫病生化防御机制的组织化学研究:II。前列腺素合成酶活性。

Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ) Pub Date : 1995-12-01

E Hadaś, L Gustowska, D Janczewska

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摘要

本文报道了旋毛虫感染小鼠肌肉中前列腺素合成酶(e.c.1.14.99.1)的组织化学定位及其在疾病不同阶段的变化动态。我们的研究表明，受感染的小鼠肌肉中前列腺素合成酶活性水平的升高可能与幼虫对肌肉的损伤程度有关，也许，酶水平的升高可以改善肌肉的功能。前列腺素合成酶的变化动态与所研究的生化、组织学和免疫学指标的变化动态相对应。

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Histochemical investigations of the biochemical defence mechanism in experimental trichinellosis: II. prostaglandin synthase activity.

In this paper, we report on the histochemical localization of prostaglandin synthase (E. C. 1.14.99.1) in mouse muscles following infection with Trichinella spiralis and the dynamics of their changes at different stages of disease. Our studies suggest that increased level of prostaglandin synthase activity in infected muscles of mice may be correlated with the degree of muscle injury by larvae and, perhaps, that increased level of enzyme ameliorates the functioning of muscle. The dynamics of prostaglandin synthase changes corresponds to the dynamic of the studied so far biochemical, histological and immunological indices.

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Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ)

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