市售的人白细胞介素-1抗体不会与猪白细胞介素-1发生交叉反应。

Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B Pub Date : 1996-07-01 DOI:10.1111/j.1439-0450.1996.tb00320.x

H Holst, U Magnusson

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引用次数: 0

摘要

白细胞介素-1 (IL-1)是炎症过程中的关键介质。市面上有几种针对人的免疫测定法，但不包括猪的IL-1。其中四种在猪标本上进行了测试。在细胞培养上清中，任何免疫测定法均未检测到IL-1，生物测定法证实IL-1活性。结果表明，人IL-1抗体与猪IL-1无交叉反应。

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Commercially available antibodies to human interleukin-1 do not crossreact with porcine interleukin-1.

Interleukin-1 (IL-1) is a key mediator in inflammatory processes. There are several immunoassays for human, but not porcine, IL-1 commercially available. Four of these were tested on porcine specimens. IL-1 was not detected, by any of the immunoassays, in cell culture supernatants with confirmed IL-1 activity in a bioassay. The results indicate that the tested antibodies to human IL-1 do not crossreact with porcine IL-1.

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Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B

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