实验研究了接种两种致龋菌后仓鼠根表面龋病的发展。

J G de Oliveira Cordeiro
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引用次数: 0

摘要

本研究的目的是在接种两种致龋细菌后,在24周内喂食高糖饮食的仓鼠,研究其根表面龋的发展情况。21日龄雄性金仓鼠103只,分为5组。4组饲喂饲料2000,1组饲喂普通饲料CE-2。在饲喂饲料2000的各组中,3组分别(AV组和SM组)或联合(AVSM组)感染粘放线菌ATCC 15987和变形链球菌NTCC 10449, 1组未感染。采用网格法评估牙菌斑积累、牙槽骨流失和牙根表面龋病。12周后,三个感染组主要在第一下颌磨牙发生根面龋。24周时,牙根表面龋病发生率在AV组最高,但牙根龋病评分在三个感染组之间无显著差异。SM组和AVSM组的磨牙冠被龋破坏严重,而AV组的磨牙冠基本完整。结果表明,粘胶放线菌攻毒是研究仓鼠根面龋的适宜方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Experimental root surface caries in hamsters the development of the disease after inoculations of two types of cariogenic bacteria.

The aim of this study was to investigate the development of root surface caries in hamsters fed a high-sucrose diet over a 24-week period after inoculations of two types of cariogenic bacteria. Twenty-one day old male golden hamsters (n = 103) were divided into 5 groups. Four groups were given diet 2000, and one group was given a stock diet CE-2, Of the groups given diet 2000, three groups were infected with Actinomyces viscosus ATCC 15987 and Streptococcus mutans NTCC 10449 separately (AV and SM groups) or in combination (AVSM group), and one group remained uninfected. A grid method was used to evaluate the plaque accumulation, alveolar bone loss, and root surface caries. After 12 weeks, root surface caries developed mainly on the first mandibular molars in the three infected groups. At 24 weeks, the prevalence of root surface caries was highest in the AV group, but root caries scores were not significantly different among the three infected groups. In the groups SM and AVSM, the molar crowns were extensively destroyed by caries, while in the AV group the crowns were almost intact. It was concluded that challenge with Actinomyces viscosus may be appropriate to study root surface caries in hamsters.

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