{"title":"[电离辐射对大鼠胰腺β细胞对链脲佐菌素耐药性的影响]。","authors":"G G Gatsko, S I Brilevskaia","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of subliminal streptozotocin doses of rat pancreas cells was studied 1 and 3 months after 1-Gy gamma irradiation. Streptozotocin injected to irradiated animals caused a drastic decrease in beta-cell function which was manifested by hyperglycemia and less intensive secretion and lesser content of insulin in isolated pancreatic islands, as compared to control.</p>","PeriodicalId":20808,"journal":{"name":"Radiobiologiia","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[The effect of ionizing radiation on the resistance of rat pancreatic beta cells to streptozotocin].\",\"authors\":\"G G Gatsko, S I Brilevskaia\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The effect of subliminal streptozotocin doses of rat pancreas cells was studied 1 and 3 months after 1-Gy gamma irradiation. Streptozotocin injected to irradiated animals caused a drastic decrease in beta-cell function which was manifested by hyperglycemia and less intensive secretion and lesser content of insulin in isolated pancreatic islands, as compared to control.</p>\",\"PeriodicalId\":20808,\"journal\":{\"name\":\"Radiobiologiia\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1993-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Radiobiologiia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiobiologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
[The effect of ionizing radiation on the resistance of rat pancreatic beta cells to streptozotocin].
The effect of subliminal streptozotocin doses of rat pancreas cells was studied 1 and 3 months after 1-Gy gamma irradiation. Streptozotocin injected to irradiated animals caused a drastic decrease in beta-cell function which was manifested by hyperglycemia and less intensive secretion and lesser content of insulin in isolated pancreatic islands, as compared to control.