[1 Gy γ辐照后期大鼠脂肪组织和肝脏质膜的理化状况。]膜的结构变化]。

Radiobiologiia Pub Date : 1993-01-01
G G Egutkin, S M Iakubovskiĭ, G G Gatsko
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引用次数: 0

摘要

在单次1-Gy γ照射后15 ~ 380天,观察大鼠脂肪组织和肝脏质膜的结构状态。通过芘实验参数、感应共振能量转移法和膜色氨酸荧光光谱特征对结构状态进行了估计。在辐照后的第50-100天,膜脂质相的微粘度增加,脂质/蛋白质相互作用的模式发生了变化,而在后来的时间里,研究中的指标与对照组没有变化。将所得数据与前两种方法的脂质含量变化进行比较,表明1-Gy辐照后,大鼠脂肪组织和肝脏质膜的理化状态在远距离发生改变。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The physicochemical status of the plasma membranes of rat fatty tissue and liver in the late periods after gamma irradiation at a dose of 1 Gy. Structural changes in the membranes].

The structural status of plasma membranes of adipose tissue and liver of rats was investigated at remote times (from 15 to 380 days) after single 1-Gy gamma irradiation. The structural status was estimated by pyrene excimerisation parameters and also by both induction resonance energy transfer method and membrane tryptophan fluorescence spectral characteristics. On days 50-100 following irradiation the microviscosity of a lipid phase of membranes increased and the mode of lipid/protein interactions changed, whereas at later times the indices under study did not vary from the controls. Comparison of the data obtained with the former results on lipid content changes indicates that the physicochemical status of plasma membranes in rat adipose tissue and liver is modified at remote times following 1-Gy gamma irradiation.

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