[消除糖尿病足的糖尿病微血管病变——真实还是错误的结论?]。

E Chantelau
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引用次数: 0

摘要

闭塞性糖尿病微血管病变如糖尿病视网膜病变和糖尿病肾病在糖尿病足中尚未明确证实。非闭塞性紊乱,如糖尿病神经病变引起的血管舒缩受损,已在糖尿病足中得到证实。然而,它们的临床相关性仍有待确定。最近的报告显示,糖尿病坏疽的组织病理学图片与脓毒性血管炎有关,而不是糖尿病微血管病变。认为足部脉搏可触及的糖尿病坏疽是由于闭塞性微血管病变,因此只能通过大截肢来治疗的假设似乎是没有根据的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Obliterating diabetic microangiopathy of the diabetic foot--reality or false conclusion?].

Occlusive diabetic microangiopathy like diabetic retinopathy and diabetic nephropathy has not been confirmed unequivocally in the diabetic foot. Non-occlusive disturbances, such as impaired vasomotion due to diabetic neuropathy, have been documented in the diabetic foot. Their clinical relevance, however, remains to be established. Recent reports have shown that the histopathological picture of diabetic gangrene is associated with septic vasculitis rather than diabetic microangiopathy. The assumption that diabetic gangrene in the presence of palpable foot pulses is due to occlusive microangiopathy and thus can be treated only by major amputation, appears to be unfounded.

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