原发性情感性精神病躁狂发作时血清肌酸激酶的浓度。

R Năstase, C Bălăiţă, C Iscrulescu, A Petrea
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引用次数: 0

摘要

本研究旨在观察患有原发性情感性疾病和躁狂发作的受试者是否表现出血清肌酸激酶浓度的改变,从而赋予其生物标志物的作用。测定了122名患有单相和双相情感性疾病的不同阶段男性患者的血清肌酸激酶浓度,以及除情感性疾病外具有不同临床形式的精神分裂症男性患者的血清肌酸激酶浓度。对照组包括60名男性。数据表明,酶浓度可以构成原发情感性疾病的生物学标志物,也可以显示疾病不同阶段(躁狂、轻躁狂、抑郁和无症状间隔)之间的差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The concentration of serum creatine-kinase in manic attacks of primary affective psychoses.

The study aims to observe whether subjects with a primary affective disease and manic attacks show modifications of serum concentration of creatine-kinase conferring it the role of a biologic marker. Serum concentration of creatine-kinase was determined for 122 men with mono- and bipolar affective disease during the different stages as well as for schizophrenic men with different clinical forms excepting the affective form. The control group included 60 men. Data indicated that enzyme concentration can constitute a biological marker for a primary affective disease also showing the differences between the different stages of the disease (mania, hypomania, depression and the symptom-free intervals).

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