类固醇激素的非转录效应。

Receptor Pub Date : 1993-01-01

I Nemere, L X Zhou, A W Norman

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引用次数: 0

摘要

越来越多的文献记录了类固醇激素的非核作用，特别是亲脂配体与特定浆体识别位点的结合。本综述收集了支持外二醇17 β、黄体酮、皮质类固醇、甲状腺激素和1,25-二羟维生素D3的膜受体存在的证据。此外，还讨论了1,25-二羟基维生素d3介导的非核信号转导机制和生理反应。

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Nontranscriptional effects of steroid hormones.

A growing body of literature exists documenting the nonnuclear effects of steroid hormones, and in particular, binding of the lipophillic ligands to specific plasmalemmal recognition sites. This review compiles evidence supporting the presence of membrane receptors for extradiol 17 beta, progesterone, corticosteroids, thyroid hormone, and 1,25-dihydroxyvitamin D3. In addition, 1,25-dihydroxyvitamin D3-mediated nonnuclear signal transduction mechanisms and physiological responses are discussed.

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Receptor

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