胎儿超声对神经母细胞瘤的产前检测。

R L Saylors, S L Cohn, E R Morgan, G M Brodeur
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引用次数: 0

摘要

目的:报告3例经产前超声诊断为神经母细胞瘤的病例,探讨产前超声诊断的肿瘤的生物学特征。患者和方法:神经母细胞瘤是新生儿最常见的肿瘤。因此,这些肿瘤中有一些是在产前形成的,应该通过母体超声检测出来。我们在此报告三例产前超声检查怀疑为神经母细胞瘤的病例。此外,我们回顾了文献中报道的另外17例病例的选择特征。结果和结论:这些数据表明,尽管大多数患者具有良好的临床和生物学特征并且表现良好,但也有一些患者表现不佳,DNA指数可能是预后最重要的预测因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prenatal detection of neuroblastoma by fetal ultrasonography.

Purpose: We report three cases of neuroblastoma diagnosed by prenatal ultrasound examination and examine the biologic features of tumors diagnosed prenatally.

Patients and methods: Neuroblastoma is the most common tumor detected in the newborn period. Thus, some of these tumors develop prenatally and should be detectable by maternal ultrasound. Here we report three cases in which a neuroblastoma was suspected on prenatal ultrasonography. In addition, we review selected features of 17 additional cases reported in the literature.

Results and conclusions: These data indicate that, although the majority of patients have favorable clinical and biological features and do well, some patients do not, and the DNA index may be the most important predictor of outcome.

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