艾滋病毒感染的长期幸存者。

Hospital practice (Office ed.) Pub Date : 1994-10-15 DOI:10.1080/21548331.1994.11443088

J A Levy

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引用次数: 37

摘要

一小部分hiv感染者的持续免疫能力反映了病毒和宿主的异质性。例如，一些HIV毒株比其他毒株更具有细胞病变性。促进更长的生存的宿主因子缺乏“增强”抗体，两种关键的CD4+细胞亚群及其细胞因子的适当平衡，以及强烈的CD8+细胞抗病毒反应。

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Long-term survivors of HIV infection.

The persistent immune competence seen in a small percentage of HIV-infected individuals reflects the heterogeneity of both the virus and the host. Some HIV strains, for example, are more cytopathic than others. Host factors that promote longer survival lack "enhancing" antibodies, an appropriate balance of two crucial CD4+ cell subsets and their cytokines, and a strong CD8+ cell antiviral response.

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Hospital practice (Office ed.)

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