22 kDa免疫双丝虫抗原对人肺双丝虫病免疫诊断的评价。

Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ) Pub Date : 1994-09-01

L Perera, A Muro, M Cordero, E Villar, F Simón

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引用次数: 0

摘要

人肺双丝蚴病通常表现为孤立的肺结节。用酶联免疫电转移印迹法鉴定了三种肺二丝虫病患者血清特异性识别的免疫二丝虫成虫22 kDa抗原。该抗原通过丙烯酰胺凝胶洗脱纯化，并在酶联免疫分析法中使用92例肺双丝虫病和其他肺部和寄生虫病患者的血清进行评估。应考虑其在人肺双丝虫病诊断中的应用。

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Evaluation of a 22 kDa Dirofilaria immitis antigen for the immunodiagnosis of human pulmonary dirofilariosis.

Human pulmonary dirofilariosis usually appears as a solitary pulmonary nodule. A 22 kDa antigen from Dirofilaria immitis adult worms specifically recognized by three sera from individuals diagnosed with pulmonary dirofilariosis was identified by enzyme-linked-immunoelectrotransfer blot. This antigen was purified by elution from acrylamide gels and evaluated in enzyme-linked immunoassay using sera from 92 patients with pulmonary dirofilariosis and other pulmonary and parasitic diseases. Its use in the diagnosis of human pulmonary dirofilariosis should be considered.

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Tropical medicine and parasitology : official organ of Deutsche Tropenmedizinische Gesellschaft and of Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ)

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