黑质内注射铁逐渐减少纹状体多巴胺代谢。

Journal of Neural Transmission - Parkinson's Disease and Dementia Section Pub Date : 1994-01-01 DOI:10.1007/BF02260941

W Wesemann, S Blaschke, M Solbach, C Grote, H W Clement, P Riederer

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引用次数: 38

摘要

在单侧神经内铁(III)(50和1.5微克)应用后1、3和6周，观察大鼠纹状体多巴胺代谢。两种浓度下，同侧纹状体神经元外3.4-二羟基苯乙酸(DOPA)水平均逐渐下降。

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Intranigral injected iron progressively reduces striatal dopamine metabolism.

The striatal dopamine metabolism of the rat was followed 1, 3, and 6 weeks after unilateral intranigral iron (III) (50- and 1.5 micrograms) application. For both concentrations a progredient decrease of extraneuronal 3.4-dihydroxyphenylacetic acid (DOPA) levels was observed in the ipsilateral striatum.

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Journal of Neural Transmission - Parkinson's Disease and Dementia Section

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