人外周血多形核白细胞的免疫复合物吞噬作用。

K Török, P Gergely, G Petrányi
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引用次数: 0

摘要

在循环免疫复合物水平升高的患者中,发现细胞内含有多形核(PMN)的免疫球蛋白的百分比增加。当将正常对照或患者的PMN白细胞与来自循环免疫复合物水平升高的患者的血清孵育时,观察到阳性细胞的增加更为明显。免疫复合物水平正常的患者的血清没有引起这种增加。由于自体和异体血清(具有较高的免疫复合物水平)增加了循环免疫复合物水平升高的患者阳性细胞的百分比,因此这些患者不太可能出现“饱和”状态。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Immune complex phagocytosis of human peripheral blood polymorphonuclear leukocytes.

An increased percentage of intracellular immunoglobulin containing-polymorphonuclear (PMN) leukocytes was found in patients with elevated level of circulating immune complexes. A more pronounced increase of positive cells was observed when PMN leukocytes of normal controls or patients were incubated in the presence of serum derived from patients with an elevated level of circulating immune complexes. Sera from patients with a normal immune complex level did not cause such an increase. Since both autologous and allogeneic serum (with higher immune complex levels) increased the percentage of positive cells of patients with elevated circulating immune complex levels, it is not likely that a "saturated" state would occur in these patients.

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