血管组织抗原免疫后豚鼠主动脉和肝脏的变化。免疫学和免疫电镜研究。

J Fehér, G Filipp, M Horváth, E Fehér
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引用次数: 0

摘要

用人血管组织抗原对豚鼠进行体液免疫反应研究,并观察主动脉和肝脏组织变化的显微和超微结构特征。免疫接种后出现了明确的体液反应。被动血凝试验在两种抗原作用之间产生交叉反应。组织学、免疫荧光和电镜检查显示内膜和肝脏结构发生变化。含igg的免疫复合物通过铁蛋白标记的单特异性抗血清在主动脉内皮和肝细胞中被证实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Aortic and hepatic changes in guinea pigs after immunization with vascular tissue antigens. Immunological and immune electron microscopic studies.

Human vascular tissue antigens were administered to guinea pigs for the study of humoral immune responses and of the microscopic and ultrastructural features of the changes produced in the aorta and liver. Immunization was followed by a definite humoral reaction. The passive haemagglutination test gave a cross reaction between the two antigenic effects. Histologic, immunofluorescent and electron microscopic studies revealed changes in the intima and the liver structure. IgG-containing immunocomplexes were demonstrable by means of ferritin-labelled monospecific antiserum in the aortic endothelium and hepatocytes.

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