根据关联诱导假说,青蛙皮肤和上皮细胞系统的主动溶质运输。

Physiological chemistry and physics Pub Date : 1981-01-01
G N Ling
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引用次数: 0

摘要

离子、糖、氨基酸等通过青蛙皮肤和其他上皮系统的运输现象通常是根据膜泵理论来解释的,根据膜泵理论,溶质分布的不对称以及进出所有活细胞的运输是由膜的渗透性和“泵”活性造成的。在本综述中,根据关联诱导假说中引入的分子机制,对溶质经上皮运输领域的某些发现进行了新的解释,根据该假说,溶质的“主动运输”只发生在双面细胞系统(如青蛙皮肤和肠上皮)中,而不是在单面细胞系统(如肌肉、神经和红细胞)中维持稳定的溶质水平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Active solute transport across frog skin and epithelial cell systems according to the association-induction hypothesis.

The phenomenon of transport of ions, sugars, amino acids, etc. across frog skin and other epithelial systems has been commonly interpreted on the basis of the membrane-pump theory, according to which asymmetry in solute distribution as well as transport into and out of all living cells results from the permeability properties and "pump" activities of the membrane. In the present review, certain findings in the field of transepithelial transport of solutes are given new interpretation on the basis of molecular mechanisms introduced in the association-induction hypothesis, according to which "active transport" of solutes occurs only across bifacial cell systems like frog skin and intestinal epithelium but not in the maintenance of steady levels of solutes in unifacial cell systems such as muscle, nerve, and red blood cells.

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