吸入133Xe测量rCBF:最近的方法进展。

Progress in nuclear medicine Pub Date : 1981-01-01
J Risberg, I Prohovnik
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引用次数: 0

摘要

综述了近年来133xe吸入法测定rCBF的方法学改进。描述了经典(Obrist)分析方法的改进,包括校正空气通道中133Xe的背景,剩余活性和污染的例程。讨论了ISI相对于双指数流动参数的优点和局限性,以及确定流动计算技术质量和可靠性的不同方法。最后,提出了一种基于傅里叶变换的曲线分析新方法。这种方法允许使用从133Xe呼吸开始的完整曲线,并提供改进的方法来纠正空气通道和动脉的影响。讨论了其灵敏度和效度较高的优点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
rCBF measurements by 133Xe inhalation: recent methodological advances.

Some recent methodological improvements of the 133Xe-inhalation method for determination of the rCBF are reviewed. Improvements of the classical (Obrist) method of analysis involving routines for correction of background, remaining activity and contamination from 133Xe in the air passages are described. Advantages and limitations of the ISI as compared to the bi-exponential flow parameters are discussed as well as different ways to determine technical quality and reliability of the flow calculations. Finally, a new method of curve analysis based on Fourier transforms is described. This method allows use of the full curve from start of 133Xe breathing and offers improved methods for correction of influence from air passages and arteries. Its advantages in terms of greater sensitivity and validity are discussed.

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