E B Raftery, M W Millar-Craig, S Mann, V Balasubramanian
{"title":"治疗对血压昼夜节律的影响。","authors":"E B Raftery, M W Millar-Craig, S Mann, V Balasubramanian","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Clinical trials of beta-blocking drugs in hypertensive subjects have shown that these drugs do not affect blood pressure significantly at night or during the early morning. Labetalol, which is a combined alpha- and beta-blocking agent, reduces mean blood pressure levels at all times. These studies strongly support the hypothesis of a circadian rhythm of alpha-receptor-mediated-sympathetic activity.</p>","PeriodicalId":75603,"journal":{"name":"Biotelemetry and patient monitoring","volume":"8 1-2","pages":"113-20"},"PeriodicalIF":0.0000,"publicationDate":"1981-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effects of treatment on circadian rhythms of blood pressure.\",\"authors\":\"E B Raftery, M W Millar-Craig, S Mann, V Balasubramanian\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Clinical trials of beta-blocking drugs in hypertensive subjects have shown that these drugs do not affect blood pressure significantly at night or during the early morning. Labetalol, which is a combined alpha- and beta-blocking agent, reduces mean blood pressure levels at all times. These studies strongly support the hypothesis of a circadian rhythm of alpha-receptor-mediated-sympathetic activity.</p>\",\"PeriodicalId\":75603,\"journal\":{\"name\":\"Biotelemetry and patient monitoring\",\"volume\":\"8 1-2\",\"pages\":\"113-20\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biotelemetry and patient monitoring\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biotelemetry and patient monitoring","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of treatment on circadian rhythms of blood pressure.
Clinical trials of beta-blocking drugs in hypertensive subjects have shown that these drugs do not affect blood pressure significantly at night or during the early morning. Labetalol, which is a combined alpha- and beta-blocking agent, reduces mean blood pressure levels at all times. These studies strongly support the hypothesis of a circadian rhythm of alpha-receptor-mediated-sympathetic activity.