冠状动脉疾病迟滞运动:左心室射血瞬时分析的证据。

European journal of cardiology Pub Date : 1981-01-01
F Cucchini, G Baldi, A L Barilli, M Di Donato, O Visioli
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引用次数: 0

摘要

对10例正常受试者(正常组)和8例冠心病患者(冠心病组)进行了整个收缩期射血期指标的瞬时测量。所有CAD组患者均从230例CAD患者中选择,因为标准射血期指标(即射血分数,EF;纤维周向缩短平均速度VcfM;平均正常化收缩期射血率(MNSER)。通过对整个射血期逐帧分析,对心室功能进行“瞬时”评估,使我们能够在这些CAD患者的收缩期早期发现心室射血异常。与对照组相比,CAD组dV/dt、dV/dt/EDV、Vcf均出现相似的峰值,且出现峰值的时间明显长于对照组;两组在收缩期结束时EF曲线分析值相近,但CAD组在射血前三分之一的平均曲线明显低于对照组。收缩期早期的节段性心室壁运动分析显示弥漫性延迟心室壁运动(迟滞运动)与逐帧射血期指数分析显示的异常有关。我们的研究结果证实,即使标准射血期指标仍在正常范围内,CAD患者在收缩期早期也可能存在心室功能异常。此外,这些异常在整个收缩期的时间表现已被清楚地评估;最后,这些数据证实了左心室射血加速作为心室功能指标的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Tardokinesis in coronary artery disease: evidence with instantaneous analysis of left ventricular ejection.

Instantaneous measurements of ejection phase indices throughout the whole systole have been performed in 10 normal subjects (normal group), and in 8 coronary artery disease (CAD) patients (CAD group). All the patients of the CAD group were selected from 230 CAD patients because of their normal values in standard ejection phase indices (i.e. ejection fraction, EF; mean velocity of circumferential fiber shortening, VcfM; mean normalized systolic ejection rate, MNSER). An 'instantaneous' evaluation of the ventricular function, by means of a frame-by-frame analysis throughout the ejection period, allowed us to detect abnormalities of ventricular ejection in the early phase of systole in these CAD patients. In comparison with the control group, the CAD group presented similar peak values of dV/dt, dV/dt/EDV and Vcf, and a significantly longer time to peak values of these indices; EF curve analysis showed similar values at the end of systole in the two groups, but the mean curve of the CAD group was significantly lower in the first third of ejection when compared with that of control group. A segmental wall motion analysis in the early phase of systole showed a diffuse delayed ventricular wall motion (tardokinesis) related to abnormalities demonstrated by frame-by-frame analysis of ejection phase indices. Our results confirm that the CAD patients may have abnormalities of ventricular performance in the early phase of systole even when standard ejection phase indices are still within the normal range. In addition, the chronological appearance of these abnormalities during the whole systole has been clearly assessed; finally, these data confirm the importance of acceleration in blood ejection from the left ventricle as an index of ventricular function.

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