{"title":"布洛芬引起低钠血症。","authors":"M Blum, A Aviram","doi":"10.1093/rheumatology/19.4.258","DOIUrl":null,"url":null,"abstract":"<p><p>A 55-year-old woman in an advanced stage of chronic renal failure due to pyelonephritis developed severe hyponatraemia after receiving 400 mg/day of ibuprofen for 3 days. The typical symptoms and the hyponatraemia disappeared when the drug was withdrawn. The likely mechanism involved and the clinical implications are discussed.</p>","PeriodicalId":76486,"journal":{"name":"Rheumatology and rehabilitation","volume":"19 4","pages":"258-9"},"PeriodicalIF":0.0000,"publicationDate":"1980-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/rheumatology/19.4.258","citationCount":"44","resultStr":"{\"title\":\"Ibuprofen induced hyponatraemia.\",\"authors\":\"M Blum, A Aviram\",\"doi\":\"10.1093/rheumatology/19.4.258\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 55-year-old woman in an advanced stage of chronic renal failure due to pyelonephritis developed severe hyponatraemia after receiving 400 mg/day of ibuprofen for 3 days. The typical symptoms and the hyponatraemia disappeared when the drug was withdrawn. The likely mechanism involved and the clinical implications are discussed.</p>\",\"PeriodicalId\":76486,\"journal\":{\"name\":\"Rheumatology and rehabilitation\",\"volume\":\"19 4\",\"pages\":\"258-9\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1980-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1093/rheumatology/19.4.258\",\"citationCount\":\"44\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rheumatology and rehabilitation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/rheumatology/19.4.258\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rheumatology and rehabilitation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/rheumatology/19.4.258","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A 55-year-old woman in an advanced stage of chronic renal failure due to pyelonephritis developed severe hyponatraemia after receiving 400 mg/day of ibuprofen for 3 days. The typical symptoms and the hyponatraemia disappeared when the drug was withdrawn. The likely mechanism involved and the clinical implications are discussed.