{"title":"近红外光谱大鼠脑监测:可能临床意义的评估。","authors":"I Giannini, M Ferrari, A Carpi, P Fasella","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Near-infrared 700-950 absorbance of some chromophores has been measured in different biological tissues, in particular rat and rabbit brain, to assess value of this noninvasive technique for monitoring of the regional functional state. Experiments carried out under different induced circulatory conditions confirmed the possibility of obtaining information on local blood content and hemoglobin oxygenation level as well as an indication of redox state of cytochrome c oxidase, the enzymatic complex that catalyzes about 95% of cellular oxygen consumption. The near IR spectral data were correlated with the result of independent simultaneous measurements of circulatory function: blood pressure, local blood flow, and local blood volume.</p>","PeriodicalId":20124,"journal":{"name":"Physiological chemistry and physics","volume":"14 3","pages":"295-305"},"PeriodicalIF":0.0000,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Rat brain monitoring by near-infrared spectroscopy: an assessment of possible clinical significance.\",\"authors\":\"I Giannini, M Ferrari, A Carpi, P Fasella\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Near-infrared 700-950 absorbance of some chromophores has been measured in different biological tissues, in particular rat and rabbit brain, to assess value of this noninvasive technique for monitoring of the regional functional state. Experiments carried out under different induced circulatory conditions confirmed the possibility of obtaining information on local blood content and hemoglobin oxygenation level as well as an indication of redox state of cytochrome c oxidase, the enzymatic complex that catalyzes about 95% of cellular oxygen consumption. The near IR spectral data were correlated with the result of independent simultaneous measurements of circulatory function: blood pressure, local blood flow, and local blood volume.</p>\",\"PeriodicalId\":20124,\"journal\":{\"name\":\"Physiological chemistry and physics\",\"volume\":\"14 3\",\"pages\":\"295-305\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1982-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Physiological chemistry and physics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physiological chemistry and physics","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Rat brain monitoring by near-infrared spectroscopy: an assessment of possible clinical significance.
Near-infrared 700-950 absorbance of some chromophores has been measured in different biological tissues, in particular rat and rabbit brain, to assess value of this noninvasive technique for monitoring of the regional functional state. Experiments carried out under different induced circulatory conditions confirmed the possibility of obtaining information on local blood content and hemoglobin oxygenation level as well as an indication of redox state of cytochrome c oxidase, the enzymatic complex that catalyzes about 95% of cellular oxygen consumption. The near IR spectral data were correlated with the result of independent simultaneous measurements of circulatory function: blood pressure, local blood flow, and local blood volume.
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