[奥硝唑在消化外科和外科重症监护中的应用[作者简介]。

Anesthesie, analgesie, reanimation Pub Date : 1981-01-01
A Delhumeau, B Carbonnelle, C Chambreuil, F L'Hoste, M Cavellat
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引用次数: 0

摘要

作者测试了奥硝唑在消化外科手术和手术复苏中的有效性。他们强调厌氧菌的频率增加以及β -内酰胺和氨基苷类抗生素在这些病原体选择中的作用。奥硝唑作为治疗性或预防性治疗使用一年。这种产品耐受性很好。在这一年中,作者注意到类杆菌菌血症的频率有所下降。他们强烈建议在创伤学中联合使用青霉素G来对抗革兰氏阴性厌氧杆菌和许多革兰氏阳性细菌。在存在厌氧革兰氏阴性消化菌群时,与庆大霉素的关联是合理的。第三代抗生素的使用往往被证明是徒劳的。建议将它们保留给在原发性院外感染中看到的最耐药的微生物。奥硝唑的处方必须遵循局灶性腹腔内感染的手术根除,特别是如果它是阑尾源性感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Ornidazole in digestive surgery and surgical intensive care (author's transl)].

The authors test the effectiveness of ornidazole in digestive surgery and surgical reanimation. They emphasize the increased frequency of anaerobic bacteria and the role of beta-lactamine and aminoside antibiotics in the selection of these pathogens. Ornidazole was used for a one year period as either a curative or prophylactic treatment. The product is very well tolerated. During the year the authors noted a decreased frequency of bacteroides bacteremia. They highly recommend the association of penicillin G in traumatology to fight gram negative anaerobic bacilli and numerous gram positive bacteria. The association with gentamycin is justified in the presence of an anaerobic gram negative digestive flora. The use of third generation antibiotics has often proved to be futile. It is recommended that they be reserved for the most resistant organisms seen in primary extra-hospital infections. The prescription of ornidazole must procede and follow the surgical eradication of focal intra-abdominal infections, especially if it is an infection of appendicular origine.

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