{"title":"新生儿败血症:粒细胞输注的可能性。","authors":"R L Wasserman","doi":"10.1080/21548331.1982.11702307","DOIUrl":null,"url":null,"abstract":"Antibiotics often fail to prevent death from overwhelming infection in the first hours, days, or weeks of life. Impaired neutrophil function seems to be the key factor in neonatal vulnerability, suggesting that improvement of neutrophil status may enhance host resistance in infected and stressed newborns. Trials of granulocyte transfusion and other “unconventional” approaches are discussed.","PeriodicalId":79221,"journal":{"name":"Hospital practice (Hospital ed.)","volume":"17 5","pages":"95-104"},"PeriodicalIF":0.0000,"publicationDate":"1982-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21548331.1982.11702307","citationCount":"9","resultStr":"{\"title\":\"Neonatal sepsis: the potential of granulocyte transfusion.\",\"authors\":\"R L Wasserman\",\"doi\":\"10.1080/21548331.1982.11702307\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Antibiotics often fail to prevent death from overwhelming infection in the first hours, days, or weeks of life. Impaired neutrophil function seems to be the key factor in neonatal vulnerability, suggesting that improvement of neutrophil status may enhance host resistance in infected and stressed newborns. Trials of granulocyte transfusion and other “unconventional” approaches are discussed.\",\"PeriodicalId\":79221,\"journal\":{\"name\":\"Hospital practice (Hospital ed.)\",\"volume\":\"17 5\",\"pages\":\"95-104\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1982-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/21548331.1982.11702307\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hospital practice (Hospital ed.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/21548331.1982.11702307\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hospital practice (Hospital ed.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/21548331.1982.11702307","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Neonatal sepsis: the potential of granulocyte transfusion.
Antibiotics often fail to prevent death from overwhelming infection in the first hours, days, or weeks of life. Impaired neutrophil function seems to be the key factor in neonatal vulnerability, suggesting that improvement of neutrophil status may enhance host resistance in infected and stressed newborns. Trials of granulocyte transfusion and other “unconventional” approaches are discussed.
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