【肺嗜酸性粒细胞增多症:目前的概念、诊断和治疗进展】。

P Durieux, P Solal-Celigny
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引用次数: 0

摘要

肺嗜酸性粒细胞增多症是一种组织嗜酸性粒细胞增多的实质性疾病(伴或不伴血液嗜酸性粒细胞增多)。无论是从病理生理学、诊断、病因学还是治疗的角度来看,它仍然不为人所知。本文对诊断方法中使用的主要分类和必要的阶段进行了评估。首先,讨论了目前对嗜酸性粒细胞功能的理解。在“寄生”、“真菌”和“药物诱导”的总标题下,对寻找精确病因诊断的方法进行了综述。然后考虑肺嗜酸性粒细胞增多伴血管炎和特发性嗜酸性粒细胞增多。作者强调建立嗜酸性粒细胞的重要性,然后考虑。作者强调建立一个精确的病因学和寻找额外的肺部病变或血管炎的证据在肺病变的管理或血管炎的证据在肺嗜酸性粒细胞增多症的管理的重要性。至于治疗,特别是长期肺嗜酸性粒细胞增多症,依赖于皮质类固醇。对一些人来说,这可能是在抗寄生虫治疗的试验之后。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Pulmonary eosinophilia: current concepts, diagnostic and therapeutic advances].

Pulmonary eosinophilia is a parenchymatous disorder with tissue eosinophilia (with or without blood eosinophilia). It remains ill understood whether from the pathophysiological, diagnostic, aetiologic or therapeutic standpoint. This paper takes stock of the principal classifications used and the necessary stages in the diagnostic approach. First, current understanding of the function of the eosinophil is discussed. The method of searching for a precise aetiological diagnosis is reviewed under the general headings of "parasitic", "fungal" and "drug induced". Pulmonary eosinophilia wih vasculitis and idiopathic eosinophilia have then considered. The authors stress the importance of establishing a eosinophilia have then considered. The authors stress the importance of establishing a precise aetiology and searching for extra pulmonary lesions or evidence of vasculitis in the management of pulmonary lesions or evidence of vasculitis in the management of pulmonary eosinophilia. As regards treatment, particularly of prolonged pulmonary eosinophilia, corticosteroids are relied upon. For some this may be after a test trial of anti-parasitic therapy.

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