无蛋白甲状旁腺提取物(PF-PTE)和γ - l-谷氨酰牛磺酸(glutaurine)对x射线诱导的高血糖大鼠的影响。

L Feuer, S Ormai
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引用次数: 0

摘要

无蛋白甲状旁腺提取物(PF-PTE)和γ - l-谷氨酰牛磺酸(glutaurine)在大鼠中产生轻度低血糖。用PF-PTE或谷胱甘肽治疗可防止154.8、219.3或258.0 mC/kg剂量x射线全身照射引起的高血糖的发生。血浆IRI值在治疗后没有改变。推测谷胱甘肽通过其对糖皮质激素的拮抗作用起作用,但也不能排除其对肠黏膜的再生作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of protein-free parathyroid extract (PF-PTE) and gamma-L-glutamyl-taurine (glutaurine) on X-ray induced hyperglycaemia in the rat.

The protein-free parathyroid extract (PF-PTE) and gamma-L-glutamyl-taurine (glutaurine) produced mild hypoglycaemia in rats. Treatment with PF-PTE or glutaurine prevented the development of hyperglycaemia induced by X-ray whole body irradiation with 154.8 or 219.3 or 258.0 mC/kg doses. The plasma IRI values did not change following treatment. It is supposed that glutaurine acts by its antagonistic effect on glucocorticoids but its regenerating effect on the intestinal mucosa cannot be excluded either.

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