{"title":"Tiaprofenic acid (suram)在膝关节和髋关节骨关节炎治疗中的应用。","authors":"J Wojtulewski, J Walter, E J Thornton","doi":"10.1093/rheumatology/20.3.177","DOIUrl":null,"url":null,"abstract":"<p><p>Tiaprofenic acid 200 mg three times a day was compared with indomethacin 25 mg three times a day in 36 patients suffering from osteoarthritis of the knee and hip. In this double-blind cross-over study little significant difference in efficacy between the drugs was seen. Although no significant difference in adverse effects was found, significantly fewer central nervous system side-effects were associated with tiaprofenic acid treatment.</p>","PeriodicalId":76486,"journal":{"name":"Rheumatology and rehabilitation","volume":"20 3","pages":"177-80"},"PeriodicalIF":0.0000,"publicationDate":"1981-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/rheumatology/20.3.177","citationCount":"10","resultStr":"{\"title\":\"Tiaprofenic acid (surgam) in the treatment of osteoarthritis of the knee and hip.\",\"authors\":\"J Wojtulewski, J Walter, E J Thornton\",\"doi\":\"10.1093/rheumatology/20.3.177\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Tiaprofenic acid 200 mg three times a day was compared with indomethacin 25 mg three times a day in 36 patients suffering from osteoarthritis of the knee and hip. In this double-blind cross-over study little significant difference in efficacy between the drugs was seen. Although no significant difference in adverse effects was found, significantly fewer central nervous system side-effects were associated with tiaprofenic acid treatment.</p>\",\"PeriodicalId\":76486,\"journal\":{\"name\":\"Rheumatology and rehabilitation\",\"volume\":\"20 3\",\"pages\":\"177-80\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1981-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1093/rheumatology/20.3.177\",\"citationCount\":\"10\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Rheumatology and rehabilitation\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/rheumatology/20.3.177\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rheumatology and rehabilitation","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/rheumatology/20.3.177","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Tiaprofenic acid (surgam) in the treatment of osteoarthritis of the knee and hip.
Tiaprofenic acid 200 mg three times a day was compared with indomethacin 25 mg three times a day in 36 patients suffering from osteoarthritis of the knee and hip. In this double-blind cross-over study little significant difference in efficacy between the drugs was seen. Although no significant difference in adverse effects was found, significantly fewer central nervous system side-effects were associated with tiaprofenic acid treatment.