[电临床和发展形式的癫痫在不同年龄阶段的表现]。

Acta neurologica latinoamericana Pub Date : 1981-01-01
H Gastaut, L Oller-Daurella
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引用次数: 0

摘要

作者回顾了不同的电临床品种和癫痫的演变,出现在六个主要年龄组:新生儿,婴儿,儿童,青少年,成人和老年。本研究的目的是回答以下问题:一方面,发现在新生儿、婴儿或幼儿中是否存在一种完全功能性的癫痫,依赖于遗传基础上遗传的体质癫痫易感性,这与其他年龄组的原发性全身性癫痫相对应。如果是这样,就要找出这种表达方式。另一方面,确认原发性全身性癫痫的发病比例是否随生活年龄的不同而不同,揭示一生中易感性的机会。作者对上述问题提出以下回答:在出生时就存在一种与体质易感性有关的主要的、功能性的癫痫。由于大脑发育不成熟,通常的电临床标准不适用于该年龄组,因此不可能识别这种变化。婴幼儿大脑的逐渐发育使得全身性癫痫的临床和电学个体化与小癫痫或大癫痫不同。这些事实使得确认主要功能性癫痫的存在成为可能,这种癫痫与青少年和较大儿童的原发性全身性癫痫相对应。癫痫易感性是导致原发性全身性癫痫的主要因素,在一生中变化很大。作者推测其发病率在每个年龄组有所不同。尽管原发性全身性癫痫的实际比例难以量化,但根据婴幼儿发生高热发作的频率,这一易感性在这一年龄组中应该很重要。在年龄较大的儿童中,可能承认癫痫易感性更大,因为原发性全身性癫痫占观察到的癫痫发作类型的三分之一以上。这种趋势在青少年中更为明显,这种形式的癫痫占患者总数的四分之三以上。在成人和老年患者中,癫痫倾向逐渐减少,可以看出原发性癫痫与其他类型癫痫的比例(年轻人25%,成年人9%,老年人1%)。(摘要删节为400字)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Electro-clinical and developmental forms of epilepsy as a function of their appearance at different ages of life].

The authors review the different electroclinical varieties and the evolution of epilepsy that appear in the six principal age groups: newborn, infancy, childhood, adolescence, adult and aged. The aim of this study is to answer the following questions: on one hand to find out if there exists in newborn, infant or young child, a form of epilepsy entirely functional, dependent on a constitutional epileptic predisposition transmitted on a genetic basis, which correspond to the primary generalized epilepsy of the other age groups. If that is so, to find out this mode of expression. On the other hand, to confirm whether the proportion of primary generalized epilepsy varies according to the different ages of life, revealing a chance in the predisposition during life. The authors propose the following answers to the above-mentioned questions: there exists at birth a principally, functional form of epilepsy in relation to a constitutional predisposition. The usual electroclinical criteria are not applicable in this age group due to brain immadurity, so it is not possible to identify this variety. The progressive development of the brain in the infant and young child permits the clinical and electrical individualization of generalized fits as distinct from Petit or Gran Mal. These facts make it possible to confirm the existence of a principally functional epilepsy which corresponds to the primary generalized epilepsy of the adolescent and older child. The epileptic predisposition, principal factor responsible for primary generalized epilepsy, varies considerably during life. The authors presume that its incidence differs in each age group. Based on the frequency of hyperthermic fits in the infant and young child, the predisposition should be important in this age group, although the actual proportion of primary generalized epilepsy is difficult to quantify. In the older child it is possible to admit that the epileptic predisposition is greater because primary generalized epilepsy represents more than a third of the types of fits observed. This tendence is even greater in adolescence, where this form of epilepsy represents over three quarters of the patients. In the adult and aged patients, the epileptic tendency diminishes progressively, as can be seen comparing the proportion of primary forms of epilepsy with other types (25% young adult, 9% mature adult and 1% in the aged).(ABSTRACT TRUNCATED AT 400 WORDS)

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