{"title":"体外分别给药和混合给药对培养的小鼠睾丸间质细胞的影响与年龄相关的雄激素分泌改变。","authors":"B Bilińska, J Musiałek-Galas","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of gonadotropic hormones on androgen level in media of cultured Leydig cells isolated from mouse testes of various age was investigated. Changes of androgen level were connected with the age of mice. The highest secretory level of androgen was found in cultures of Leydig cells from mature 60 day old animals, which then decreased in 7 month old mice. Stimulating effect of LH and PRL on hormonal secretion by cultured Leydig cells was observed.</p>","PeriodicalId":75854,"journal":{"name":"Folia histochemica et cytochemica","volume":"21 1","pages":"33-43"},"PeriodicalIF":0.0000,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of in vitro administration of LH, prolactin separately, and LH and prolactin in mixture on cultured Leydig cells from mouse testes: II. Age-related alterations of androgen secretion.\",\"authors\":\"B Bilińska, J Musiałek-Galas\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The effect of gonadotropic hormones on androgen level in media of cultured Leydig cells isolated from mouse testes of various age was investigated. Changes of androgen level were connected with the age of mice. The highest secretory level of androgen was found in cultures of Leydig cells from mature 60 day old animals, which then decreased in 7 month old mice. Stimulating effect of LH and PRL on hormonal secretion by cultured Leydig cells was observed.</p>\",\"PeriodicalId\":75854,\"journal\":{\"name\":\"Folia histochemica et cytochemica\",\"volume\":\"21 1\",\"pages\":\"33-43\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1983-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Folia histochemica et cytochemica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Folia histochemica et cytochemica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effect of in vitro administration of LH, prolactin separately, and LH and prolactin in mixture on cultured Leydig cells from mouse testes: II. Age-related alterations of androgen secretion.
The effect of gonadotropic hormones on androgen level in media of cultured Leydig cells isolated from mouse testes of various age was investigated. Changes of androgen level were connected with the age of mice. The highest secretory level of androgen was found in cultures of Leydig cells from mature 60 day old animals, which then decreased in 7 month old mice. Stimulating effect of LH and PRL on hormonal secretion by cultured Leydig cells was observed.