[1982年全球结核病造成的问题]。

P Chaulet, N A Khaled, R Amrane
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引用次数: 0

摘要

结核杆菌发现一百年后,与结核病的斗争在世界范围内仍然存在许多问题。每年出现1000万新病例:近500万具有高度传染性;95%的病例来自发展中国家。目前有效的官方通报系统并不完善,但通过对结核病的系统调查对年度感染风险进行估算,可以提供有关问题规模及其在每个国家演变时间尺度的准确信息。这是目前可获得的最佳流行病学指数。与结核病作斗争的技术问题在理论上得到了解决:以细菌学实验室网络为中心,对高危人群进行选择性检测,能够识别所有感染源;化疗,变得越来越安全,持续时间最多减少到6或9个月,几乎100%的患者治愈;正确接种卡介苗可降低婴儿结核病的风险。操作问题仍然是最严重的。最大的困难出现在发病率最高的国家:它们与全球资源短缺有关,但有时也与现有资源利用不良有关。协调一致的国际行动可使所有国家获得抗结核药物和适当的卫生技术。如果明智地利用现有的信息和手段,每个国家今天都可以实现有效的国家抗结核规划。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Problems posed by tuberculosis in the world in 1982].

One hundred years after the discovery of the tubercle bacillus the struggle against tuberculosis still poses numerous problems on a world scale. Each year, 10 million new cases appear: nearly five million are highly contagious; 95% of these cases come from developing countries. The official notification system currently in force is imperfect but a reckoning of the annual infection risk, from a methodical enquiry into tuberculous disease gives exact information on the size of the problem and its evolutionary time scale in each country. This is the best epidemiological index currently available. The technical problems of the struggle against tubercle are resolved in theory: the selective detection of groups at risk, centered on a network of bacteriology laboratories enables identification of all the sources of infection; chemotherapy, becoming safer and safer, with a duration reduced to 6 or 9 months at the maximum and curing practically 100% of the patients; properly performed BCG vaccination reduces the risk of infantile tuberculosis. Operational problems remain the most serious. The greatest difficulties are seen in countries with the highest prevalence: they are linked to a global shortage of resources but also at times a poor utilisation of the resources available. A concerted international action could render antituberculous drugs and the appropriate sanitary technology to all countries. With a judicious use of available information and means each country could today achieve an effective national antituberculous programme.

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