多组分疫苗与福尔马林灭活细胞疫苗对水貂铜绿假单胞菌出血性肺炎地方性流行的防护效果比较。

C Abe, J Y Homma, H Noda, R Yanagawa, K Morihara, H Tsuzuki, S Takeuchi
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引用次数: 0

摘要

用铜绿假单胞菌n10 (E型)的共同抗原(OEP)和蛋白酶、弹性酶类毒素组成的多组分疫苗与福尔马林杀死的n10细胞对水貂铜绿假单胞菌引起的出血性肺炎的保护效果进行了比较。一次接种多组分疫苗(OEP、蛋白酶类毒素和弹性酶类毒素各100微克),可以明显预防水貂中由铜绿假单胞菌(血清型G)引起的出血性肺炎的流行性,而接种福尔马林杀伤细胞在预防流行病方面的效果要差得多。两种疫苗之间的死亡率差异是显著的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of the effects of a multi-component vaccine and a formalin-killed cell vaccine on protection against enzootic of hemorrhagic pneumonia due to Pseudomonas aeruginosa in mink.

Effectiveness of a multi-component vaccine consisting of the common antigen (OEP) derived from Pseudomonas aeruginosa strain N 10 (serotype E) and toxoids of protease and elastase was compared with that of formalin-killed cells of strain N 10 on protection against enzootic of hemorrhagic pneumonia due to P. aeruginosa in mink. One administration of the multi-component vaccine (100 microgram each of OEP, protease toxoid and elastase toxoid) clearly prevented enzootic of hemorrhagic pneumonia due to P. aeruginosa (serotype G) in mink, while a vaccination of formalin-killed cells was much less effective in preventing an epidemic. The difference in mortality rates between two vaccines was remarkable.

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