从成年小鼠培养的红系前体对H2O2毒性敏感。

In Vitro Pub Date : 1984-04-01 DOI:10.1007/BF02618592

M F Grasset, J P Blanchet

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引用次数: 0

摘要

使用Iscove改良的Dulbecco液体培养基，可抑制成人骨髓中晚红细胞前体(CFU-Es)的生长。过氧化氢酶和其他破坏H2O2的化合物恢复培养基支持菌落发育的能力。然而，来自成人骨髓和胎儿肝脏的早期前体cfu - e对H2O2具有抗性。

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Erythroid precursors cultured from adult mice are sensitive to H2O2 toxicity.

The growth of late erythroid precursors (CFU-Es) from adult bone marrow is inhibited when Iscove 's modified Dulbecco's medium supplied in liquid form is used. Catalase and other H2O2 destroying compounds restore the capacity of culture medium to support colony development. However early precursors from adult bone marrow and fetal liver CFU-Es were resistant to H2O2.

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In Vitro

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